• Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: A longitudinal study of the Nordic JIA cohort 

      Glerup, Mia; Thiel, Steffen; Rypdal, Veronika Gjertsen; Arnstad, Ellen Dalen; Ekelund, Maria; Peltoniemi, Suvi; Aalto, Kristiina; Rygg, Marite; Nielsen, Susan; Fasth, Anders; Berntson, Lillemor; Nordal, Ellen Berit; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-09)
      <i>Background</i> - To determine the serum levels of the lectin pathway proteins early in the disease course and 17 years after disease onset and to correlate the protein levels to markers of disease activity in participants from a population-based Nordic juvenile idiopathic arthritis (JIA) cohort. Additionally, to assess the predictive value of lectin pathway proteins with respect to remission ...
    • Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients 

      Smedbråten, Julia; Mjøen, Geir; Hartmann, Anders; Åsberg, Anders; Rollag, Halvor; Mollnes, Tom Eirik; Sandvik, Leiv; Fagerland, Morten W.; Thiel, Steffen; Sagedal, Solbjørg (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-18)
      Background: Higher incidence of malignancy and infectious diseases in kidney transplant recipients is related to immunosuppressive treatment after transplantation and the recipient’s native immune system. The complement system is an essential component of the innate immunity. The aim of the present study was to investigate the association of effector molecules of the lectin complement pathway with ...
    • M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis 

      Brix, Ninna; Glerup, Mia; Thiel, Steffen; Mistegaard, Clara Elbæk; Skals, Regitze Gyldenholm; Berntson, Lillemor; Fasth, Anders; Nielsen, Susan Mary; Nordal, Ellen Berit; Rygg, Marite; Hasle, Henrik; Albertsen, Birgitte Klug; Herlin, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)
      Objective: Distinction on clinical grounds between acute lymphoblastic leukaemia presenting with arthropathy (ALLarthropathy) and juvenile idiopathic arthritis (JIA) is difficult, as the clinical and paraclinical signs of leukaemia may be vague. The primary aim was to examine the use of lectin complement pathway proteins as markers to differentiate ALLarthropathy from JIA. The secondary aims were ...